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Xymogen HistDAO, Supports Healthy Histamine Digestion and Digestive Comfort, 60 Delayed Release Tablets Antioxidants milk thistle and turmeric haveXymogen HistDAO Details Xymogen HistDAO provides DAO (diamine oxidase) the natural enzyme your body uses to break down histamine from food in the digestive tract in a delayed release tablet. For people who are sensitive to histamine rich foods, supplementing DAO before meals can support healthy histamine digestion and digestive comfort. The delayed release tablet helps the DAO enzyme reach the small intestine, where dietary histamine is broken down.